REPIN1 antibody (Middle Region)

Catalog No. ABIN404770

This Rabbit Polyclonal antibody specifically detects REPIN1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit, Dog and Saccharomyces cerevisiae.

Quick Overview for REPIN1 antibody (Middle Region) (ABIN404770)

Target: REPIN1 (Replication Initiator 1 (REPIN1))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REPIN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-REPIN1 Antibody

Binding Specificity: Middle Region

Sequence: GNCGRSFAQW DQLVAHKRVH VAEALEEAAA KALGPRPRGR PAVTAPRPGG

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%

Characteristics: This is a rabbit polyclonal antibody against REPIN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human REPIN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 567 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for REPIN1

Target: REPIN1 (Replication Initiator 1 (REPIN1))

Alternative Name: REPIN1

Background: Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. REPIN1 binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT sequence of opposite orientation situated within the OBR zone. REPIN1 facilitates DNA bending.
Alias Symbols: AP4, RIP60, ZNF464, Zfp464
Protein Interaction Partner: UBC, NEDD8, SUMO1, SUZ12, RNF2, BMI1, NEK9, MYCBP, POLA2, HGS, Dlg4, TERF2, GATA3, HDAC2, HDAC1, GMNN, HDAC3,
Protein Size: 567

Molecular Weight: 63 kDa

Gene ID: 29803

NCBI Accession: NM_013400, NP_037532

UniProt: Q9BWE0