HSFY1 antibody (Middle Region)

Catalog No. ABIN405269

The Rabbit Polyclonal anti-HSFY1 antibody has been validated for WB. It is suitable to detect HSFY1 in samples from Human.

Quick Overview for HSFY1 antibody (Middle Region) (ABIN405269)

Target: HSFY1 (Heat Shock Transcription Factor, Y-Linked 1 (HSFY1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSFY1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HSFY1 Antibody

Binding Specificity: Middle Region

Sequence: VSVNEAPYRN MLPAGNPWLQ MPTIADRSAA PHSRLALQPS PLDKYHPNYN

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against HSFY1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSFY1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 401 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSFY1

Target: HSFY1 (Heat Shock Transcription Factor, Y-Linked 1 (HSFY1))

Alternative Name: HSFY1

Background: HSFY1 is a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region, this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms.This gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region, this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: HSF2L, HSFY, HSFY2
Protein Interaction Partner: HNRNPF, QRICH1, RBM47, SV2B, GCM2, TBX6, SOX15, RBFOX1, HSFY2, E2F7, RABEP1, PPM1A, NDUFS1, AIF1, HOXA1,
Protein Size: 401

Molecular Weight: 45 kDa

Gene ID: 86614

NCBI Accession: NM_033108, NP_149099

UniProt: Q96LI6