SLC6A2 antibody (Middle Region)

Catalog No. ABIN405431

Product Details anti-SLC6A2 Antibody

Target: SLC6A2 (Solute Carrier Family 6 (Neurotransmitter Transporter, Noradrenalin), Member 2 (SLC6A2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: STLSGSTFWA VVFFVMLLAL GLDSSMGGME AVITGLADDF QVLKRHRKLF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC6A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLC6A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 617 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC6A2 antibody (ABIN405431)

Bayles, Harikrishnan, Lambert, Baker, Agrotis, Guo, Jowett, Esler, Lambert, El-Osta: "Epigenetic modification of the norepinephrine transporter gene in postural tachycardia syndrome." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 32, Issue 8, pp. 1910-6, (2012) (PubMed).

Suzuki, Matsumoto, Oshino, Kamata, Goto, Otani: "Combination of the serotonin transporter and norepinephrine transporter gene promoter polymorphisms might influence harm avoidance and novelty seeking in healthy females." in: Neuroscience letters, Vol. 439, Issue 1, pp. 52-5, (2008) (PubMed).

Target Details for SLC6A2

Target: SLC6A2 (Solute Carrier Family 6 (Neurotransmitter Transporter, Noradrenalin), Member 2 (SLC6A2))

Alternative Name: SLC6A2 (SLC6A2 Products)

Background: The SLC6A2 gene encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis.The SLC6A2 gene encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis (Kim et al., 2006 [PubMed 17146058]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NAT1, NET, NET1, SLC6A5
Protein Interaction Partner: SNCA, ACTB, STX1A, PPP2R1A,
Protein Size: 617

Molecular Weight: 69 kDa

Gene ID: 6530

NCBI Accession: NM_001043, NP_001034

UniProt: P23975