UPP1 antibody (N-Term)

Catalog No. ABIN405444

This anti-UPP1 antibody is a Rabbit Polyclonal antibody detecting UPP1 in WB. Suitable for Human, Mouse, Rat, Cow, Horse, Zebrafish (Danio rerio) and Guinea Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for UPP1 antibody (N-Term) (ABIN405444)

Target: UPP1 (Uridine Phosphorylase 1 (UPP1))

Reactivity: Human, Mouse, Rat, Cow, Horse, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UPP1 Antibody

Binding Specificity: N-Term

Sequence: AATGANAEKA ESHNDCPVRL LNPNIAKMKE DILYHFNLTT SRHNFPALFG

Predicted Reactivity: Cow: 85%, Guinea Pig: 75%, Horse: 83%, Human: 100%, Mouse: 85%, Rat: 85%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against UPP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UPP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 310 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-UPP1 antibody (ABIN405444)

Temmink, de Bruin, Laan, Turksma, Cricca, Masterson, Noordhuis, Peters: "The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells." in: The international journal of biochemistry & cell biology, Vol. 38, Issue 10, pp. 1759-65, (2006) (PubMed).

Target Details for UPP1

Target: UPP1 (Uridine Phosphorylase 1 (UPP1))

Alternative Name: UPP1

Background: UPP1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Alias Symbols: UDRPASE, UP, UPASE, UPP
Protein Interaction Partner: CTDP1, YRDC, WDR45B, WBP2, UCK2, UBE2D1, MPST, UBC, EBNA-LP, VIM,
Protein Size: 310

Molecular Weight: 34 kDa

Gene ID: 7378

NCBI Accession: NM_003364, NP_003355

UniProt: Q16831

Pathways: Ribonucleoside Biosynthetic Process