GPR6 antibody (N-Term)

Catalog No. ABIN405451

This Rabbit Polyclonal antibody specifically detects GPR6 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for GPR6 antibody (N-Term) (ABIN405451)

Target: GPR6 (G Protein-Coupled Receptor 6 (GPR6))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GPR6 Antibody

Binding Specificity: N-Term

Sequence: NASAASLNDS QVVVVAAEGA AAAATAAGGP DTGEWGPPAA AALGAGGGAN

Predicted Reactivity: Cow: 86%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against GPR6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GPR6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 362 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPR6

Target: GPR6 (G Protein-Coupled Receptor 6 (GPR6))

Alternative Name: GPR6

Background: GPR6 belongs to the G-protein coupled receptor 1 family.It is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Alias Symbols: -
Protein Size: 362

Molecular Weight: 38 kDa

Gene ID: 2830

NCBI Accession: NM_005284, NP_005275

UniProt: P46095