SPOCK3 antibody (Middle Region)

Catalog No. ABIN405715

This Rabbit Polyclonal antibody specifically detects SPOCK3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig and Rabbitand has been mentioned in 1 publication.

Quick Overview for SPOCK3 antibody (Middle Region) (ABIN405715)

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPOCK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPOCK3 Antibody

Binding Specificity: Middle Region

Sequence: CPCPSDKPTS TSRNVKRACS DLEFREVANR LRDWFKALHE SGSQNKKTKT

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SPOCK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPOCK3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 433 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SPOCK3 antibody (ABIN405715)

Lutter, Xie, Tatin, Makinen: "Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation." in: The Journal of cell biology, Vol. 197, Issue 6, pp. 837-49, (2012) (PubMed).

Target Details for SPOCK3

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Alternative Name: SPOCK3

Background: Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 is a member of a novel Ca(2+)-binding proteoglycan familyProteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 encodes a member of a novel Ca(2+)-binding proteoglycan family.[supplied by OMIM].
Alias Symbols: HSAJ1454, TES-3, TICN3
Protein Interaction Partner: SPOCK2, MMP14, MMP3,
Protein Size: 433

Molecular Weight: 49 kDa

Gene ID: 50859

NCBI Accession: NM_001040159, NP_001035249

UniProt: B3KR67

Pathways: Glycosaminoglycan Metabolic Process