Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ) antibody

Antigen: Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Human, Rat (Rattus), Mouse (Murine)

Application: Western Blotting (WB)

Catalog no.: ABIN405821

Additional Information

Alternative name: PIGQ

Gene ID: PIGQ

UniProt: B2RAU6

Immunogen: The immunogen for anti-PIGQ antibody: synthetic peptide directed towards the N terminal of human PIGQ

Sequence: PTVLPDRQAGATTASTGGLAAVFDTVARSEVLFRSDRFDE GPVRLSHWQS

Cross-Reactivity: Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)

Format: Lyophilized

Reconstitution: Add 50 µl of distilled water. Final anti-PIGQ antibody concentration is 1 mg/ml.

Description: PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ is a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).

Characteristics: Antigen Size: 581 amino acids

Molecular Weight: 65kDa

Application Details

Application Notes: WB Suggested Anti-PIGQ Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate.

Purification: Affinity Purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Research Area: Signaling, Fatty Acids

Restrictions: For Research Use only

Images

WB Suggested Anti-PIGQ Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate

Publications

Product: Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).