ASB12 antibody (C-Term)

Catalog No. ABIN406223

The Rabbit Polyclonal anti-ASB12 antibody has been validated for WB. It is suitable to detect ASB12 in samples from Human, Mouse, Rat, Dog, Horse, Rabbit, Cow and Guinea Pig.

Quick Overview for ASB12 antibody (C-Term) (ABIN406223)

Target: ASB12 (Ankyrin Repeat and SOCS Box-Containing 12 (ASB12))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASB12 Antibody

Binding Specificity: C-Term

Sequence: DDKGIALLLQ ARATPRSLLS QVRLVVRRAL CQAGQPQAIN QLDIPPMLIS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ASB12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ASB12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 309 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB12

Target: ASB12 (Ankyrin Repeat and SOCS Box-Containing 12 (ASB12))

Alternative Name: ASB12

Background: ASB12 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The SOCS box domain has not yet been annotated for the protein. The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The SOCS box domain has not yet been annotated for this encoded protein.
Alias Symbols: FLJ39577
Protein Interaction Partner: ACTB, DHX36, CADPS2, SRRT, MTHFD1L, NUDT21, RBM6, DHX38, PRDX6, AIFM1, RBM10, RCN2, PFN2, PFN1, PFKFB3, MYH10, KRT8, GLO1, FGG, CKB, TUFM, TCEB2, TCEB1, SFPQ, RPL38, LZTR1, RNF7, CUL5,
Protein Size: 309

Molecular Weight: 34 kDa

Gene ID: 142689

NCBI Accession: NM_130388, NP_569059

UniProt: Q8WXK4