»
Antibodies
»
anti-Apolipoprotein E (APOE) antibody
Apolipoprotein E (APOE) antibody
| Antigen |
|
| Synonyms |
AD2, LPG, LDLCQ5, MGC1571, AI255918, APOEA, APOE, ad2, apoprotein, MGC110064, im:7036787, wu:fb69a05, zgc:110064, apoe |
| Clonality |
Monoclonal (E3) |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
 Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
Western Blotting (WB) (45), Enzyme Immunoassay (EIA) (22), ELISA (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Immunohistochemistry (Frozen Sections) (IHC (fro)) (8), Immunodiffusion (ID) (6), Immunohistochemistry (IHC) (6), Radioimmunoassay (RIA) (6), Immunoprecipitation (IP) (5), Immunoelectrophoresis (IEP) (2), Radial Immunodiffusion (RID) (2), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Ouchterlony Double Diffusion (ODD) (1), Thin Layer Immunoassay (TIA) (1), To be determined by user (TBD) (1)
|
| Catalog no. |
ABIN452452 |
| Quantity |
50 µg |
| Price |
360.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Characteristics
|
Synonyms: ApoE, Apo-E
|
|
Alternative name
|
Apolipoprotein E (Apo E)
|
|
Gene ID
|
348
|
|
Swiss-Prot
|
P02649
|
|
Immunogen
|
Human apolipoprotein E
|
|
Cross-Reactivity
|
Human
|
|
Isotype
|
IgG1 (Matching secondary antibodies)
|
|
Clone
|
E3
|
|
Description
|
Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoproteinconstituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster withAPOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, ortype III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol andtriglycerides are the consequence of impaired clearance of chylomicron and VLDLremnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease byaffecting amyloid-beta deposition.
|
|
Specificity
|
This antibody reacts with all isoforms E2, E3, E4 of Human apolipoprotein E (ApoE). Species: Human. Others not tested.
|
|
Application Notes
|
ELISA. Western Blot: 1/200 with PBS, pH 7.4. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
|
|
Purification
|
Aff - Purified
|
|
Storage
|
Prior to reconstitution store at 2-8°C. Following reconstitution store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
|
|
Research Area
|
Metabolism
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Apolipoprotein E (APOE)", type "Antibodies"
|
Hosts
|
Goat (32), Rabbit (21), Mouse (14)
|
|
Reactivities
|
Human (43), Mouse (Murine) (4), Rabbit (4), Hamster (3), Rat (Rattus) (2), Chimpanzee (1)
|
|
Applications
|
Western Blotting (WB) (45), Enzyme Immunoassay (EIA) (22), ELISA (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Immunohistochemistry (Frozen Sections) (IHC (fro)) (8), Immunodiffusion (ID) (6), Immunohistochemistry (IHC) (6), Radioimmunoassay (RIA) (6), Immunoprecipitation (IP) (5), Immunoelectrophoresis (IEP) (2), Radial Immunodiffusion (RID) (2), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Ouchterlony Double Diffusion (ODD) (1), Thin Layer Immunoassay (TIA) (1), To be determined by user (TBD) (1)
|
|
Conjugates
|
Biotin (3), HRP (1)
|
|
Epitopes
|
C-Term (4)
|
