NOS1AP antibody (N-Term)

Catalog No. ABIN453979

This Goat Polyclonal antibody specifically detects NOS1AP in IHC (p) and EIA. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for NOS1AP antibody (N-Term) (ABIN453979)

Target: NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))

Reactivity: Human, Mouse, Rat, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This NOS1AP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-NOS1AP Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to CAPON.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence PSKTKYNLVDDGH-C, from the N Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/8000. Immunohistochemistry on paraffin sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for NOS1AP

Target: NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))

Alternative Name: NOS1AP

Background: CAPON is a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins.Synonyms: CAPON, Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, KIAA0464

Gene ID: 9722

NCBI Accession: NP_055512

UniProt: O75052