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Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP) (N-Term) antibody

Details for Product No. ABIN453979, Supplier: Login to see
Antigen
  • MGC78853
  • Capon
  • MGC145362
  • 6330408P19Rik
  • CAPON
Epitope
N-Term
16
13
13
10
5
3
3
2
2
2
1
1
1
1
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
64
17
16
2
1
Host
Goat
43
17
5
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
35
29
16
14
11
8
1
1
1
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Immunogen Peptide with sequence PSKTKYNLVDDGH-C, from the N Terminus of the protein sequence
Specificity This antibody reacts to CAPON.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name NOS1AP (NOS1AP Antibody Abstract)
Background CAPON is a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins.Synonyms: CAPON, Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, KIAA0464
Gene ID 9722
NCBI Accession NP_055512
UniProt O75052
Pathways
Application Notes Peptide ELISA: 1/8000. Immunohistochemistry on paraffin sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP) (N-Term) antibody (ABIN453979) anti-Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP) (N-Term) antibody
Background publications Jaffrey, Snowman, Eliasson et al.: "CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95." in: Neuron, Vol. 20, Issue 1, pp. 115-24, 1998 (PubMed).