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Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP) (N-Term) antibody

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Synonyms MGC78853, Capon, MGC145362, 6330408P19Rik, CAPON
(16), (13), (13), (10), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(64), (17), (16), (2), (1)
(43), (17), (5)
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(35), (29), (16), (14), (11), (8), (1), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide with sequence PSKTKYNLVDDGH-C, from the N Terminus of the protein sequence
Specificity This antibody reacts to CAPON.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name NOS1AP (NOS1AP Antibody Abstract)
Background CAPON is a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins.Synonyms: CAPON, Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, KIAA0464
Gene ID 9722
NCBI Accession NP_055512
UniProt O75052
Application Notes Peptide ELISA: 1/8000. Immunohistochemistry on paraffin sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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 image for anti-Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP) (N-Term) antibody (ABIN453979) anti-Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP) (N-Term) antibody
Background publications Jaffrey, Snowman, Eliasson et al.: "CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95." in: Neuron, Vol. 20, Issue 1, pp. 115-24, 1998 (PubMed).

Catalog No. ABIN453979
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