Tacrolimus (FK506) antibody

Catalog No. ABIN472100

The Mouse Monoclonal anti-Tacrolimus antibody is suitable to detect Tacrolimus. It has been validated for ELISA.

Quick Overview for Tacrolimus (FK506) antibody (ABIN472100)

Target: Tacrolimus (FK506)

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA

Clone: FK1

Product Details

Specificity: Detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogeneic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.

Purification: Purified

Immunogen: FK-506-BSA conjugate.

Isotype: IgM

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris buffered saline, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details

Target: Tacrolimus (FK506)

Alternative Name: FK506 / Tacrolimus

Target Type: Chemical

Background: Name/Gene ID: FK506

Synonyms: FK506