PKD2 antibody (AA 871-883)

Catalog No. ABIN477978

The Goat Polyclonal anti-PKD2 antibody (ABIN477978) specifically detects PKD2 in WB and ELISA. The antibody is reactive with Human, Mouse, Cow, Dog, Horse, Monkey, Bat, Hamster and Xenopus laevis samples.

Quick Overview for PKD2 antibody (AA 871-883) (ABIN477978)

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reactivity: Human, Mouse, Cow, Dog, Horse, Monkey, Bat, Hamster, Xenopus laevis

Host: Goat

Clonality: Polyclonal

Conjugate: This PKD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PKD2 Antibody

Binding Specificity: AA 871-883

Specificity: Human PKD2.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Opossum, Xenopus (100%) Rat, Pig, Turkey, Chicken (92%) Lizard, Stickleback, Medaka, Pufferfish, Zebrafish (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-ERAKLKRREVLGR from an internal region of human PKD2 (NP_000288.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Opossum, Xenopus (100%), Rat, Pig, Turkey, Chicken (92%), Lizard, Stickleback, Medaka, Pufferfish, Zebrafish (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA, WB (1 - 3 μg/mL)

Usage: Western Blot: Approx 100kD band observed in lysates of cell line HeLa (calculated MW of 110kD according to NP_000288.1). Recommended concentration: 1-3 μg/mL.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for PKD2

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Alternative Name: PKD2 / Polycystin 2

Background: Name/Gene ID: PKD2
Subfamily: Calcium channel - TRP
Family: Ion Channel

Synonyms: PKD2, APKD2, Pc-2, Polycystic kidney disease 2, Polycystwin, PC2, PKD4, Polycystin-2, R48321, TRPP2

Gene ID: 5311

NCBI Accession: NP_000288

UniProt: Q13563

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity