MHC Class II antibody

Catalog No. ABIN481690

This Rat Monoclonal antibody specifically detects MHC Class II in IHC and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for MHC Class II antibody (ABIN481690)

Target: MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This MHC Class II antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: ER-TR3

Product Details anti-MHC Class II Antibody

Specificity: MHC Class II antigens are heterodimers consisting of one a- chain (31-34  kDa) and one beta-chain (26-29  kDa). The epitope has not been further characterized. Antigen distribution Isolated cells: The antigen is found on dendritic cells, B-cells and macrophages. The level of antigen detected by ER-TR1, ER-TR2 and ER-TR3 differs from strain to strain (see table below). Tissue Sections: The antigen is found on B-cells, interdigitating cells and macrophages in peripheral lymphoid organs but is absent from T-cells. It is also expressed as a fine reticular pattern on stromal thymic cells of the cortex and as a confluent pattern on stromal thymic cells of the medulla. Specificity: Mouse: cells expressing MHC class II antigens Other species: negative on human, other unknown

Purification: Affinity purified

Immunogen: murine thymic reticulum

Application Details

Application Notes: Approved: IHC, IHC-Fr (1:200)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 0.5 mL distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 5 mg/mL BSA, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for MHC Class II

Target: MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))

Alternative Name: MHC Class II