Follicular Dendritic Cells antibody

Catalog No. ABIN481696

This Mouse Monoclonal antibody specifically detects Follicular Dendritic Cells in IHC (p) and IHC. It exhibits reactivity toward Rat.

Quick Overview for Follicular Dendritic Cells antibody (ABIN481696)

Target: Follicular Dendritic Cells

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Follicular Dendritic Cells antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)

Clone: Ki-M9R

Product Details anti-Follicular Dendritic Cells Antibody

Specificity: Ki-M9R detects a 49  kDa cytoplasmic antigen. The epitope has not been further characterized. Antigen distribution: Isolated cells: Ki-M9R is negative with all peripheral blood cells and cells of the bone marrow or peritoneal cavity. Tissue sections: Ki-M9R specifically recognizes antigen trapping macrophages of the B-cell system such as sinus lining cells and dendritic reticulum cells. It is also positive on splenic metallophils. Macrophages in T-cell areas are negative with Ki- M9R. None of the macrophages in non-lymphoid organs are detected by Ki-M 9R. No cross-reactivity was found with other cell types at different tissue sites except with hepatic sinusoids. In vivo adminstration of Ki-M9R reveals a direct cytotoxicity to, and the elimation of Ki-M9R positive cells. Animals survive this treatment. Specificity: Rat: subpopulation of macrophages. Other species: not tested Comments: During the course of an infection the number of antigen trapping cells decreases while the number of antigen presenting cells increases. Antigen presenting Ki-M4R Ki-M9R Antigen trapping Course of an infection Unpublished data raised in The Institute of Pathology, Michaelisstrasse 11, 2300 Kiel, Germany

Purification: Affinity purified

Immunogen: Peritoneal macrophages

Application Details

Application Notes: Approved: IHC, IHC-P (1:200)

Usage: For IHC-P per treatment with Proteinase K is recommended.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C.

Target Details for Follicular Dendritic Cells

Target: Follicular Dendritic Cells