ABL1 antibody (pTyr245)

Catalog No. ABIN482036

The Rabbit Polyclonal anti-ABL1 antibody is suitable to detect ABL1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for ABL1 antibody (pTyr245) (ABIN482036)

Target: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ABL1 Antibody

Binding Specificity: AA 196-245, pTyr245

Specificity:

c-Abl (Phospho-Tyr245) Antibody detects endogenous levels of c-Abl only when phosphorylated at Tyr245.

PhosphorylationH:Y245 M:Y245 R:Y245

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human c-Abl around the phosphorylation site of Tyr245.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000

Comment:

Unigene-Number: Hs.431048 (NCBI Gene Symbol: ABL1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for ABL1

Target: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Alternative Name: C-Abl

Background:

Synonyms: ABL1, JTK7, Proto-oncogene tyrosine-protein kinase ABL1, c-ABL, p150

NCBI Gene Symbol: ABL1

Molecular Weight: 122 kDa

Gene ID: 25

OMIM: 189980

UniProt: P00519

Pathways: Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism