CAD antibody (pThr456)

Catalog No. ABIN482742

The Rabbit Polyclonal anti-CAD antibody (ABIN482742) specifically detects CAD in IHC and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for CAD antibody (pThr456) (ABIN482742)

Target: CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAD antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-CAD Antibody

Binding Specificity: AA 422-471, pThr456

Specificity:

CAD (Phospho-Thr456) Antibody detects endogenous levels of CAD only when phosphorylated at Thr456.

PhosphorylationH:T456 M:T456

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CAD around the phosphorylation site of Thr456.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:5000

Comment:

Unigene-Number: Hs.377010 (NCBI Gene Symbol: CAD)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CAD

Target: CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))

Alternative Name: CAD

Background:

Synonyms: CAD protein, glutamine-dependent carbamoyl-phosphate synthase, PYR1

NCBI Gene Symbol: CAD

Molecular Weight: 242 kDa

Gene ID: 790

OMIM: 114010

UniProt: P27708

Pathways: Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process