PAR1 antibody (Cleaved-Ser42)

Catalog No. ABIN486774

The Rabbit Polyclonal anti-PAR1 antibody (ABIN486774) specifically detects PAR1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for PAR1 antibody (Cleaved-Ser42) (ABIN486774)

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PAR1 Antibody

Binding Specificity: AA 23-72, Cleaved-Ser42

Specificity:

PAR1 (Cleaved-Ser42) Antibody detects endogenous levels of fragment of activated PAR1 resulting from cleavage adjacent to Ser42.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PAR1.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:20000

Comment:

Unigene-Number: Hs.482562 (NCBI Gene Symbol: F2R)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PAR1

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Alternative Name: PAR1

Background:

Synonyms: chemokine orphan receptor 1, CXCR-7, CXCR7, G-protein coupled receptor 159, G-protein coupled receptor RDC1, RDC1

NCBI Gene Symbol: F2R

Molecular Weight: 46 kDa

Gene ID: 2149

OMIM: 187930

UniProt: P25116

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus