TLE4 antibody (N-Term)

Catalog No. ABIN486927

This anti-TLE4 antibody is a Rabbit Polyclonal antibody detecting TLE4 in WB and IHC. Suitable for Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for TLE4 antibody (N-Term) (ABIN486927)

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TLE4 Antibody

Binding Specificity: N-Term

Sequence: GAEKHRNSAD YSSESKKQKT EEKEIAARYD SDGEKSDDNL VVDVSNEDPS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TLE4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 773 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TLE4

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Alternative Name: TLE4

Background: TLE4 is the transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: BCE-1, E(spI), ESG, ESG4, GRG4, BCE1
Protein Interaction Partner: SRPK2, POU2F2, UBC, LIG4, BRCA1, WDR77, PRMT5, PPM1B, CUX1, OTX1, OTX2, TLE4, PAX5, POU2F1, MSX1, HDAC1,
Protein Size: 773

Molecular Weight: 84 kDa

Gene ID: 7091

NCBI Accession: NM_007005, NP_008936

UniProt: Q04727

Pathways: WNT Signaling