Morphine-6 antibody
| Antigen |
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| Clonality |
Polyclonal |
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Host
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Application
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| Catalog no. |
ABIN487782 |
| Quantity |
0.1 ml (8.0mg/ml (U.V. abs @ 280nm)) (Variants) |
| Price |
645.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: Morphine 6, (5a, 6a)-7, 8-didehydro-4, 5-epoxy-17-methylmorphinan-3, 6-diol
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Immunogen
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Morphine (6)-BSA
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta,and kappa opioid receptors that regulate stress perception, pain control, reward behavior,and neurohormone secretion in reward-relevant brain systems. It has the highest affinityfor mu, followed by delta and kappa. Rapid activation of the mu opioid receptor bymorphine results in a euphoric phenotype, thus conferring the reinforcing effects of thedrug. This activation is accompanied by extracellular dopamine release, which altersseveral events related to the cAMP signal transduction pathway. Of particular significanceis that CREB seems to be modified by morphine, thereby affecting addictive behavioralphenomena, such as withdrawal symptoms.
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Specificity
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This antibody reacts to Morphine (6).
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Application Notes
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ELISA: 0.5μg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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8.0mg/ml (U.V. abs @ 280nm)
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Purification
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Ig Fraction
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Buffer
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20mM Phosphate, 150mM Sodium Chloride, pH 7.2 containing 0.09%Sodium Azide as preservative
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Storage
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Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Drugs
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Restrictions
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For Research Use only
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Alternatives for antigen "Morphine-6", type "Antibodies"