PANK2 antibody

Catalog No. ABIN2728202

There are 5+ publications for this product available. The Mouse Monoclonal anti-PANK2 antibody is suitable to detect PANK2 in samples from Human, Rat, Dog and Monkey. It has been validated for WB, IHC, IF and FACS.

Quick Overview for PANK2 antibody (ABIN2728202)

Target: PANK2 (Pantothenate Kinase 2 (PANK2))

Reactivity: Human, Rat, Dog, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This PANK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 3H9

Product Details anti-PANK2 Antibody

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PANK2(NP_705902) produced in HEK293T cell.

Isotype: IgG2a

Application Details

Application Notes: WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-PANK2 antibody (ABIN2728202)

Santambrogio, Dusi, Guaraldo, Rotundo, Broccoli, Garavaglia, Tiranti, Levi: "Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients." in: Neurobiology of disease, (2015) (PubMed).

Huang, Chu, Jiang, Chen, Zhang, Zeng: "Glycyrrhizin suppresses lung adenocarcinoma cell growth through inhibition of thromboxane synthase." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 33, Issue 2, pp. 375-88, (2014) (PubMed).

Zeman, Lin, Freire, Cimprich: "DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis." in: The Journal of cell biology, Vol. 206, Issue 2, pp. 183-97, (2014) (PubMed).

Barrett, Fang, Gargano, Markovich, Kocarek, Runge-Morris: "Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 3'-phosphoadenosine-5'-phosphosulfate deficiency." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 8, pp. 1505-13, (2013) (PubMed).

Brunetti, Dusi, Morbin, Uggetti, Moda, DAmato, Giordano, dAmati, Cozzi, Levi, Hayflick, Tiranti: "Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model." in: Human molecular genetics, Vol. 21, Issue 24, pp. 5294-305, (2012) (PubMed).

Target Details for PANK2

Target: PANK2 (Pantothenate Kinase 2 (PANK2))

Alternative Name: PANK2

Molecular Weight: 59.1 kDa

Gene ID: 80025

NCBI Accession: NM_153638

HGNC: 80025

Pathways: Ribonucleoside Biosynthetic Process