SAMHD1 antibody

Catalog No. ABIN2731368

This Mouse Monoclonal antibody specifically detects SAMHD1 in WB, IF and FACS. It exhibits reactivity toward Human and Monkey. It has been mentioned in 4+ publications

Quick Overview for SAMHD1 antibody (ABIN2731368)

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This SAMHD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 1F6

Product Details anti-SAMHD1 Antibody

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-SAMHD1 antibody (ABIN2731368)

Hofmann, Vanwalscappel, Bloch, Landau: "TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes." in: Retrovirology, Vol. 13, Issue 1, pp. 83, (2017) (PubMed).

Martin-Gayo, Buzon, Ouyang, Hickman, Cronin, Pimenova, Walker, Lichterfeld, Yu: "Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers." in: PLoS pathogens, Vol. 11, Issue 6, pp. e1004930, (2015) (PubMed).

Tabler, Lucera, Haqqani, McDonald, Migueles, Connors, Tilton: "CD4+ memory stem cells are infected by HIV-1 in a manner regulated in part by SAMHD1 expression." in: Journal of virology, Vol. 88, Issue 9, pp. 4976-86, (2014) (PubMed).

Zhang, Bloch, Nguyen, Kim, Landau: "SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e89558, (2014) (PubMed).

Target Details for SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Alternative Name: SAMHD1

Molecular Weight: 72.0 kDa

Gene ID: 25939

NCBI Accession: NM_015474

HGNC: 25939