PAR1 antibody (AA 24-37)

Catalog No. ABIN490018

This Goat Polyclonal antibody specifically detects PAR1 in WB, ELISA, IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PAR1 antibody (AA 24-37) (ABIN490018)

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PAR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PAR1 Antibody

Binding Specificity: AA 24-37

Specificity: Human F2R / Thrombin receptor.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla (100%) Gibbon, Baboon, Monkey (93%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-TRARRPESKATNAT from an internal region (near N-terminus) of human F2R / Thrombin receptor (NP_001983.2). Percent identity by BLAST analysis: Human, Gorilla (100%), Gibbon, Baboon, Monkey (93%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (2.5 μg/mL), Peptide-ELISA (1:3200), WB (0.5 - 2 μg/mL)

Usage: Approx 48  kDa band observed in lysates of cell line HeLa (calculated MW of 47.4  kDa according to NP_001983.2).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for PAR1

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Alternative Name: F2R / Thrombin Receptor / PAR1

Background: Name/Gene ID: F2R
Subfamily: Proteinase-activated
Family: GPCR

Synonyms: F2R, CF2R, Coagulation factor II receptor, PAR1, PAR-1, Thrombin receptor, TR, HTR, Protease-activated receptor 1

Gene ID: 2149

NCBI Accession: NP_001983

UniProt: P25116

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus