C1QC antibody

Catalog No. ABIN499050

The Rabbit Polyclonal anti-C1QC antibody (ABIN499050) specifically detects C1QC in WB and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for C1QC antibody (ABIN499050)

Target: C1QC (Complement Component 1, Q Subcomponent, C Chain (C1QC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C1QC Antibody

Specificity: This antibody detects endogenous levels of C1q-C protein. (region surrounding Gln119)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for C1QC

Target: C1QC (Complement Component 1, Q Subcomponent, C Chain (C1QC))

Alternative Name: C1q C Subunit

Background: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.Synonyms: C1QG, Complement 1qA, Complement C1q subcomponent subunit C, Complement C1qC

Molecular Weight: approx. 30 kDa

Gene ID: 714

NCBI Accession: NP_001107573

UniProt: P02747

Pathways: Complement System