GJA4 antibody

Catalog No. ABIN499077

The Rabbit Polyclonal anti-GJA4 antibody (ABIN499077) specifically detects GJA4 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GJA4 antibody (ABIN499077)

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GJA4 Antibody

Specificity: This antibody detects endogenous levels of Connexin 37 protein. (region surrounding Leu116)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GJA4

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Alternative Name: GJA4 / Cx37

Background: The Connexin 37/GJA4 gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.Synonyms: Connexin-37, Gap junction alpha-4 protein

Molecular Weight: approx. 36.0 kDa

Gene ID: 2701

NCBI Accession: NP_002051

UniProt: P35212

Pathways: Cell-Cell Junction Organization