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Characteristics
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Synonyms: ADAMTS-like 5, thrombospondin type I domain containing 6, THSD6
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Alternative name
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ADAMTSL5
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Gene ID
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339366
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Swiss-Prot
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Q6ZMM2
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Immunogen
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ADAMTSL5 antibody was raised against a 17 amino acid peptide near the carboxy terminusof human ADAMTSL5. (ABIN499212)
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Cross-Reactivity
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Human, Mouse (Murine), Rat (Rattus)
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Isotype
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IgG (Matching secondary antibodies)
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Description
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ADAMTSL5 belongs to a large superfamily containing 20 ADAMTS proteases and at leasteight ADAMTS-like proteins. ADAMTS proteases are secreted enzymes with a conservedorganization that includes a metalloprotease domain and an ancillary domain containingone or more thrombospondin type 1 repeats (TSR). The ADAMTS-like subfamily comprisesproteins homologous to the ADAMTS ancillary domains but lacking the protease domainand hence lacking catalytic activity. The exact role of ADAMTSL5 is currently unknown, butother ADAMTS-like proteins appear to have regulatory roles in the extracellular matrix.
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Specificity
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This antibody reacts to ADAMTSL5 near the carboxy terminus. Species: Human, Mouse, Rat. Others not tested. Add. Information: Blocking peptide available: blocking peptide (ABIN499212)
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