CDIP1 antibody (Center)

Catalog No. ABIN499607

The Rabbit Polyclonal anti-CDIP1 antibody has been validated for WB, IF, IHC (p) and EIA. It is suitable to detect CDIP1 in samples from Human and Mouse.

Quick Overview for CDIP1 antibody (Center) (ABIN499607)

Target: CDIP1 (LITAF-Like Protein (CDIP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CDIP1 Antibody

Binding Specificity: Center

Specificity: This antibody reacts to CDIP.

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the center of Human CDIP

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CDIP antibody can be used for detection of CDIP at 0.25 - 0.5 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CDIP1

Target: CDIP1 (LITAF-Like Protein (CDIP1))

Alternative Name: LITAF-Like Protein

Background: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.Synonyms: C16orf5, CDIP, Cell death-inducing protein, Transmembrane protein I1

Gene ID: 29965

NCBI Accession: NP_037531

UniProt: Q9H305