SCARA5 antibody (C-Term)

Catalog No. ABIN500680

This Rabbit Polyclonal antibody specifically detects SCARA5 in WB, IF and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for SCARA5 antibody (C-Term) (ABIN500680)

Target: SCARA5 (Scavenger Receptor Class A, Member 5 (SCARA5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCARA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-SCARA5 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects SCARA5.

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: A 17 amino acid peptide near the carboxy terminus of Human SCARA5. Genename: SCARA5

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for SCARA5

Target: SCARA5 (Scavenger Receptor Class A, Member 5 (SCARA5))

Alternative Name: SCARA5

Background: Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARA5 is a cell-surface receptor that contains that collagen-like domain and N-terminal scavenger receptor cysteine rich domain typical of the class A scavenger receptor subfamily. Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low density lipoprotein. Instead, SCARA5 binds serum ferritin and mediates its endocytosis from the cell surface, indicating SCARA5 may play a role in non-transferrin iron delivery. At least four isoforms of SCARB1 are known to exist.Synonyms: Scavenger receptor class A member 5

Gene ID: 286133

NCBI Accession: NP_776194

UniProt: Q6ZMJ2

Pathways: Transition Metal Ion Homeostasis