TARBP1 antibody (Center)

Catalog No. ABIN501032

The Rabbit Polyclonal anti-TARBP1 antibody has been validated for WB and EIA. It is suitable to detect TARBP1 in samples from Human and Mouse.

Quick Overview for TARBP1 antibody (Center) (ABIN501032)

Target: TARBP1 (TAR (HIV-1) RNA Binding Protein 1 (TARBP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TARBP1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TARBP1 Antibody

Binding Specificity: Center

Specificity: This antibody detects TARBP1 at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogen: TRBP1 antibody was raised against a 17 amino acid peptide from near the center of human TRBP1.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for TARBP1

Target: TARBP1 (TAR (HIV-1) RNA Binding Protein 1 (TARBP1))

Alternative Name: TARBP1

Background: The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1alpha (EF-1alpha), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.Synonyms: Probable methyltransferase TARBP1, TAR RNA-binding protein 1, TAR RNA-binding protein of 185 kDa, TRM3, TRP-185, TRP185

Gene ID: 6894

NCBI Accession: NP_005637