TARBP1 antibody (AA 1571-1621)

Catalog No. ABIN7449839

Product Details anti-TARBP1 Antibody

Target: TARBP1 (TAR (HIV-1) RNA Binding Protein 1 (TARBP1))

Binding Specificity: AA 1571-1621

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TARBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-TARBP1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1571 and 1621

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TARBP1

Target: TARBP1 (TAR (HIV-1) RNA Binding Protein 1 (TARBP1))

Alternative Name: TARBP1 (TARBP1 Products)

Synonyms: Tarbp1 antibody, Gm179 antibody, TARBP1 antibody, TRM3 antibody, TRP-185 antibody, TRP185 antibody, TAR RNA binding protein 1 antibody, TAR (HIV-1) RNA binding protein 1 antibody, Tarbp1 antibody, TARBP1 antibody, tarbp1 antibody

Background: Background: TAR RNA-binding protein 1 (TARBP1) is a probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. TARBP1 may act by methylating HIV-1 TAR RNA [taken from the Universal Protein Resource (UniProt) Q13395].

Gene ID: 6894

NCBI Accession: NP_005637

UniProt: Q13395