DLX4 antibody (Middle Region)

Catalog No. ABIN501637

This Rabbit Polyclonal antibody specifically detects DLX4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Pig, Rabbit and Guinea Pig.

Quick Overview for DLX4 antibody (Middle Region) (ABIN501637)

Target: DLX4 (Distal-Less Homeobox 4 (DLX4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLX4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLX4 Antibody

Binding Specificity: Middle Region

Sequence: RTFSVSPCSP PLPSLWDLPK AGTLPTSGYG NSFGAWYQHH SSDVLASPQM

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 93%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against DLX4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DLX4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 168 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DLX4

Target: DLX4 (Distal-Less Homeobox 4 (DLX4))

Alternative Name: DLX4

Background: Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
Alias Symbols: BP1, DLX7, DLX8, DLX9
Protein Interaction Partner: LSM3, MAGED1,
Protein Size: 168

Molecular Weight: 19 kDa

Gene ID: 1748

NCBI Accession: NM_001934, NP_001925

UniProt: Q92988