Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa (CSTF2) (N-Term) antibody

Details for Product No. ABIN501955
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Antigen
Synonyms CSTF2, CstF-64, fb11e07, zgc:56346, zgc:77730, wu:fb11e07, 64kDa, C630034J23Rik, Cstf64, CSFT64, cstF-64, cstf-64
Epitope
N-Term
(15), (7), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
(51), (27), (12), (12), (12), (1)
Host
Rabbit
(46), (6), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(42), (24), (14), (10), (9), (7), (4), (4), (2)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN501955
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human CSTF2
Sequence VDPEIALKIL HRQTNIPTLI AGNPQPVHGA GPGSGSNVSM NQQNPQAPQA
Predicted Reactivity Human : 100 %, Rabbit : 100 %, Guinea pig : 80 %, Horse : 80 %, Mouse : 80 %, Rat : 80 %, Bovine : 80 %, Dog : 80 %
Characteristics This is a rabbit polyclonal antibody against CSTF2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CSTF2
Background CSTF2 is a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.
Molecular Weight 61 kDa
Gene ID 1478
NCBI Accession NP_001316, NM_001325
UniProt P33240
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 577 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa (CSTF2) (N-Term) antibody WB Suggested Anti-CSTF2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 293T cell lysate
Background publications Lim, Hao, Shaw et al.: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, 2006 (PubMed).

Validation Images
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