CSTF2 antibody (N-Term)

Catalog No. ABIN501955

This Rabbit Polyclonal antibody specifically detects CSTF2 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig and Horse.

Quick Overview for CSTF2 antibody (N-Term) (ABIN501955)

Target: CSTF2 (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa (CSTF2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSTF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CSTF2 Antibody

Binding Specificity: N-Term

Sequence: VDPEIALKIL HRQTNIPTLI AGNPQPVHGA GPGSGSNVSM NQQNPQAPQA

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CSTF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CSTF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 577 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CSTF2

Target: CSTF2 (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa (CSTF2))

Alternative Name: CSTF2

Background: CSTF2 is a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CstF-64
Protein Interaction Partner: UBQLN1, SPAG8, SS18L1, TFG, HGS, RBBP6, ZNF341, UBC, WWOX, rev, LSM8, GET4, BABAM1, AKAP2, MAP4, CDKN2A, PARN, BARD1, CPSF2, CPSF3, CPSF6, NUP153, MAX, EIF4B, DDX1, DDB1, CSTF3, APP, UBQLN4, POLR2A, CDC73, SRRM1, UL48, KIAA1377, EEF1G, FEZ1, SYMPK, CHD3,
Protein Size: 577

Molecular Weight: 61 kDa

Gene ID: 1478

NCBI Accession: NM_001325, NP_001316

UniProt: P33240