Lamin B1 (LMNB1) antibody
| Antigen |
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| Synonyms |
LMN, ADLD, LMN2, LMNB, MGC111419, fc06g01, wu:fc06g01, MGC52550, Lamin-L(I), lmn, lmn2, lmnb, LMNB1, MGC165937, LOC100037680 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Human, Rat (Rattus), Mouse (Murine)
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Application
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| Catalog no. |
ABIN502713 |
| Quantity |
50 µg |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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Lamin-B1 (LMNB1)
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Gene ID
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LMNB1
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UniProt
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P20700
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Immunogen
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The immunogen for anti-LMNB1 antibody: synthetic peptide directed towards the middle region of human LMNB1
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Sequence
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EEVAQRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQGTP RASNRSCAIM
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Cross-Reactivity
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Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-LMNB1 antibody concentration is 1 mg/ml.
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Description
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LAMNB1 encodes for one of the two B type proteins of the nuclear lamina, B1. The Vertebrate lamins consist of two types, A and B. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Characteristics
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Antigen Size: 586 amino acids
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Molecular Weight
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66kDa
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Application Notes
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WB Suggested Anti-LMNB1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: SK-MEL-2 cell lysate.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Research Area
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Cytoskeleton
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Restrictions
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For Research Use only
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Product
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Lee, Seng, Sekine et al.: "Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1." in: PLoS medicine, Vol. 4, Issue 6, pp. e186, 2007 (PubMed).
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Alternatives for antigen "Lamin B1 (LMNB1)", type "Antibodies"
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Hosts
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Rabbit (31), Mouse (16)
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Reactivities
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Human (42), Rat (Rattus) (21), Mouse (Murine) (20), Cow (Bovine) (6), Dog (Canine) (6), Rabbit (5), Sheep (Ovine) (5), Zebrafish (Danio rerio) (3), Chicken (2), Cat (Feline) (1)
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Applications
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Western Blotting (WB) (47), ELISA (28), Immunohistochemistry (IHC) (15), Immunofluorescence (IF) (14), Immunocytochemistry (ICC) (10), Immunoprecipitation (IP) (9), Flow Cytometry (FACS) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2)
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Epitopes
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C-Term (9), N-Term (3), pThr575 (2), Internal Region (1)
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