GNA12 antibody (Middle Region)

Catalog No. ABIN503576

The Rabbit Polyclonal anti-GNA12 antibody has been validated for WB. It is suitable to detect GNA12 in samples from Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow and Zebrafish (Danio rerio).

Quick Overview for GNA12 antibody (Middle Region) (ABIN503576)

Target: GNA12 (Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12))

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNA12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNA12 Antibody

Binding Specificity: Middle Region

Sequence: TFQLYVPALS ALWRDSGIRE AFSRRSEFQL GESVKYFLDN LDRIGQLNYF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against GNA12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GNA12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 381 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GNA12

Target: GNA12 (Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12))

Alternative Name: GNA12

Background: GNA12 belongs to the G-alpha family. G(12) subfamily. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Alias Symbols: MGC104623, MGC99644, NNX3, RMP, gep
Protein Interaction Partner: GNB3, ARAF, UBC, IL3RA, APP, LRRK2, SUMO1, PCK1, PPP2R1A, ARHGEF11, ARHGEF12, S1PR5, AKAP13, GNA13, GNA12, S1PR4, TSHR, NAPA, RASA2, PPP5C, TEC, BTK, CDH1, TBXA2R, F2R, PRKCA, HSP90AA1, GNB1, DRD5, CDH2, CDH15, ACTB, ARHGEF28, MAP3K5, RHOA, PRKCD, PRKCB,
Protein Size: 381

Molecular Weight: 44 kDa

Gene ID: 2768

NCBI Accession: NM_007353, NP_031379

UniProt: Q03113