Proenkephalin (PENK) antibody

Antigen: Proenkephalin (PENK)

Synonyms: ENK, PPA, Penk1, AI326464, PENK, penk, MGC134476, Enk, Penk2, Penk-rs, MGC93514, zgc:73353, Penk, MGC107924

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Catalog no.: ABIN504046

Additional Information

Alternative name: Proenkephalin-A (PENK)

Gene ID: PENK

UniProt: P01210

Immunogen: The immunogen for anti-PENK antibody: synthetic peptide directed towards the middle region of human PENK

Sequence: DAEEDDSLANSSDLLKELLETGDNRERSHHQDGSDNEEEV SKRYGGFMRG

Cross-Reactivity: Human

Format: Lyophilized

Reconstitution: Add 50 µl of distilled water. Final anti-PENK antibody concentration is 1 mg/ml.

Description: Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK (114-133) and PENK (237-258) increase glutamate release in the stri

Characteristics: Antigen Size: 267 amino acids

Molecular Weight: 31kDa

Application Details

Application Notes: WB Suggested Anti-PENK Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate.

Purification: Affinity Purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

WB Suggested Anti-PENK Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate

Publications

Product: Nikoshkov, Drakenberg, Wang et al.: "Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 2, pp. 786-91, 2008 (PubMed).