KDM5B antibody (AA 231-319)

Catalog No. ABIN524186

There is 1 publication for this product available. The Mouse Monoclonal anti-KDM5B antibody is suitable to detect KDM5B in samples from Human. It has been validated for WB and ELISA.

Quick Overview for KDM5B antibody (AA 231-319) (ABIN524186)

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KDM5B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1G10

Product Details anti-KDM5B Antibody

Binding Specificity: AA 231-319

Purpose: Mouse monoclonal antibody raised against a partial recombinant KDM5B.

Sequence: AKRMRAEAMN IKIEPEETTE ARTHNLRRRM GCPTPKCENE KEMKSSIKQE PIERKDYIVE NEKEKPKSRS KKATNAVDLY VCLLCGSGN

Cross-Reactivity: Human

Immunogen: KDM5B (NP_006609, 231 a.a. ~ 319 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In ascites fluid

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-KDM5B antibody (ABIN524186)

Hayami, Yoshimatsu, Veerakumarasivam, Unoki, Iwai, Tsunoda, Field, Kelly, Neal, Yamaue, Ponder, Nakamura, Hamamoto: "Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway." in: Molecular cancer, Vol. 9, pp. 59, (2010) (PubMed).

Target Details for KDM5B

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Alternative Name: KDM5B

Background: Full Gene Name: jumonji, AT rich interactive domain 1B
Synonyms: FLJ10538,FLJ12459,FLJ12491,FLJ16281,FLJ23670,KDM5B,PLU-1,PUT1,RBBP2H1A

Gene ID: 10765

NCBI Accession: NP_006609, NM_006618

Pathways: Warburg Effect