ATP7B antibody (AA 1372-1465)

Catalog No. ABIN560009

There is 1 publication for this product available. The Mouse Monoclonal anti-ATP7B antibody is suitable to detect ATP7B in samples from Human. It has been validated for WB and ELISA.

Quick Overview for ATP7B antibody (AA 1372-1465) (ABIN560009)

Target: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATP7B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3E10

Product Details anti-ATP7B Antibody

Binding Specificity: AA 1372-1465

Purpose: Mouse monoclonal antibody raised against a partial recombinant ATP7B.

Sequence: QLKCYKKPDL ERYEAQAHGH MKPLTASQVS VHIGMDDRWR DSPRATPWDQ VSYVSQVSLS SLTSDKPSRH SAAADDDGDK WSLLLNGRDE EQYI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ATP7B (NP_000044, 1372 a.a. ~ 1465 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ATP7B antibody (ABIN560009)

Ansede, Wright, St Claire, Hart, Gefroh, Brouwer: "Characterization of sandwich-cultured hepatocytes as an in vitro model to assess the hepatobiliary disposition of copper." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 5, pp. 969-76, (2009) (PubMed).

Target Details for ATP7B

Target: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Alternative Name: ATP7B

Background: Full Gene Name: ATPase, Cu++ transporting, beta polypeptide
Synonyms: PWD,WC1,WD,WND

Gene ID: 540

NCBI Accession: NM_000053

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process