Chloride Channel 2 (CLCN2) (AA 38-387) antibody

Details for Product No. ABIN560397
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Antigen
Synonyms CLCN2, CLC2, LOC100150892, AL118368, ClC-2, Clc2, nmf240, CLC-2, CIC-2, ECA2, ECA3, EGI11, EGI3, EGMA, EJM6, EJM8, clC-2
Epitope
AA 38-387
(10), (8), (8), (5), (3), (3), (2), (1), (1)
Reactivity
Human
(47), (23), (21), (14), (14), (12), (12), (2), (1), (1)
Host
Mouse
(32), (9), (8)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), ELISA, RNA Interference (RNAi)
(34), (22), (10), (10), (7), (4), (2), (1), (1), (1), (1)
Pubmed 4 references available
Quantity 100 μg
Shipping to United States (Change)
Availability Will be delivered in 11 to 12 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN560397
394.24 $
Plus shipping costs $45.00 and $26.40 dry ice

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Immunogen CLCN2 (AAH21578.1, 38 a.a. ~ 387 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: TVSTAVIVFELTGQIAHILP VMIVVILANAVAQSLQPSLY DSIIRIKKLPYLPELGWGRH QQYRVRVEDIMVRDVPHVAL SCTFRDLRLALHRTKGRMLA LVESPESMILLGSIERSQVV ALLGAQLSPARRRQHMQERR ATQTSPLSDQEGPPTPEASV CFQVNTEDSAFPAARGETHK PLKPALKRGPSVTRNLGESP TGSAESAGIALRSLFCGSPP PEAASEKLESCEKRKLKRVR ISLASDADLEGEMSPEETHT IFSLLGVDHAYVTSIGRLIG IVTLKELRKAIEGSVTAQGV KVRPPLASFRDSATSSSDTE TTEVHALWGPHSRHGLPREG SPSDSDDKCQ
Clone 3E1
Isotype IgG2a kappa
Characteristics Mouse monoclonal antibody raised against a full length recombinant CLCN2.
Alternative Name CLCN2
Background Gene: chloride channel 2
Synonyms: CIC-2, CLC2, ECA3, EGI3, EGMA
Gene ID 1181
Application Notes Application specialization: Cell lysate, Recombinant protein, Transfected lysate
Restrictions For Research Use only
Buffer 1x PBS, pH 7.2
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
anti-Chloride Channel 2 (CLCN2) (AA 38-387) antibody CLCN2 monoclonal antibody (M01), clone 3E1 Western Blot analysis of CLCN2 expression in Hela S3 NE (ABIN1339524).
anti-Chloride Channel 2 (CLCN2) (AA 38-387) antibody (2) Western blot analysis of CLCN2 over-expressed 293 cell line, cotransfected with CLCN2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with CLCN2 monoclonal antibody (M01), clone 3E1 (ABIN560397). GAPDH (36.1 kDa) used as specificity and loading control.
anti-Chloride Channel 2 (CLCN2) (AA 38-387) antibody (3) Western Blot analysis of CLCN2 expression in transfected 293T cell line by CLCN2 monoclonal antibody (M01), clone 3E1.

Lane 1: CLCN2 transfected lysate(96.8 kDa).
Lane 2: Non-transfected lysate.
anti-Chloride Channel 2 (CLCN2) (AA 38-387) antibody (4) Western Blot detection against Immunogen (64.24 kDa) .
Product cited in: Alessi, Andjelkovic, Caudwell et al.: "Mechanism of activation of protein kinase B by insulin and IGF-1." in: The EMBO journal, Vol. 15, Issue 23, pp. 6541-51, 1997 (PubMed).

Datta, Dudek, Tao et al.: "Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery." in: Cell, Vol. 91, Issue 2, pp. 231-41, 1997 (PubMed).

Cantley, Neel: "New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 8, pp. 4240-5, 1999 (PubMed).

Kandel, Hay: "The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB." in: Experimental cell research, Vol. 253, Issue 1, pp. 210-29, 1999 (PubMed).

Validation Images
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