TCR alpha/beta antibody (FITC)

Catalog No. ABIN567988

This Mouse Monoclonal antibody specifically detects TCR alpha/beta in FACS. It exhibits reactivity toward Human.

Quick Overview for TCR alpha/beta antibody (FITC) (ABIN567988)

Target: TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCR alpha/beta antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: IP26

Product Details anti-TCR alpha/beta Antibody (FITC)

Cross-Reactivity (Details): Species reactivity (tested):Human

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE! This product is photosensitive and should be protected from light.

Storage: 4 °C

Target Details for TCR alpha/beta

Target: TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))

Alternative Name: T Cell Receptor / TCR alpha/beta

Background: The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.