FOXC1 antibody (Internal Region)

Catalog No. ABIN569579

The Goat Polyclonal anti-FOXC1 antibody is suitable to detect FOXC1 in samples from Human, Mouse and Pig. It has been validated for WB and EIA.

Quick Overview for FOXC1 antibody (Internal Region) (ABIN569579)

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Reactivity: Human, Mouse, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This FOXC1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-FOXC1 Antibody

Binding Specificity: Internal Region

Sequence: C-DAVKDKEEKD RLH

Specificity: Recognizes FOXC1 (internal).

Cross-Reactivity (Details): Species reactivity (expected):Pig, Mouse.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Dynthetic peptide from an internal region of Human FOXC1 (NP_001444.2). Genename: FOXC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FOXC1

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Alternative Name: FOXC1 / FKHL7 / FREAC3

Background: FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.Synonyms: FREAC-3, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3

Molecular Weight: 56.8kDa (NP_001444.2).

Gene ID: 2296

NCBI Accession: NP_001444

UniProt: Q12948

Pathways: Chromatin Binding, Glycosaminoglycan Metabolic Process