RBM20 antibody (AA 717-727)

Catalog No. ABIN569613

The Goat Polyclonal anti-RBM20 antibody (ABIN569613) specifically detects RBM20 in WB and EIA. The antibody is reactive with Human, Mouse, Rat and Cow samples.

Quick Overview for RBM20 antibody (AA 717-727) (ABIN569613)

Target: RBM20 (RNA Binding Motif Protein 20 (RBM20))

Reactivity: Human, Mouse, Rat, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This RBM20 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-RBM20 Antibody

Binding Specificity: AA 717-727

Sequence: C-QLDKAELDER P

Specificity: Recognizes RBM20 (717-727).

Cross-Reactivity (Details): Species reactivity (expected):Human, Rat, Cow.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Synthetic peptide corresponding to internal sequence amino acids 717-727 of Human RBM20 (NP_001127835.1).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RBM20

Target: RBM20 (RNA Binding Motif Protein 20 (RBM20))

Alternative Name: RBM20

Background: Defects in RBM20 are the cause of cardiomyopathy dilated type 1DD (CMD1DD) [MIM:613172]. A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. RBM20 is expressed in the heart and contains 1 RRM (RNA recognition motif) domain.Synonyms: RNA binding motif protein 20

Molecular Weight: 130kDa (Mouse NP_001164318.1).

Gene ID: 282996

NCBI Accession: NP_001127835

UniProt: Q5T481