PCSK5 antibody (Internal Region)

Catalog No. ABIN570691

This Goat Polyclonal antibody specifically detects PCSK5 in ELISA. It exhibits reactivity toward Human.

Quick Overview for PCSK5 antibody (Internal Region) (ABIN570691)

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PCSK5 antibody is un-conjugated

Application: ELISA

Grade: Recent

Product Details anti-PCSK5 Antibody

Binding Specificity: Internal Region

Purpose: PCSK5

Sequence: PDGSYQDTKK NLCRK

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence PDGSYQDTKKNLCRK, from the internal region of the protein sequence according to NP_006191.2.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Preliminary experiments in lysates of cell lines K562 and MOLT4 gave no specific signal but low background (at antibody concentration up to 1 μg/mL). We would appreciate any feedback from people in the field - have any results been reported

Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for PCSK5

Target: PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))

Alternative Name: PCSK5

Background: PCSK5, proprotein convertase subtilisin/kexin type 5, PC5, PC6, PC6A, SPC6, OTTHUMP00000063532, prohormone convertase 5, proprotein convertase PC5, protease PC6, subtilisin/kexin-like protease PC5

Gene ID: 5125

NCBI Accession: NP_006191

Pathways: Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones