CA2 antibody

Catalog No. ABIN576211

This Sheep Polyclonal antibody specifically detects CA2 in WB and ID. It exhibits reactivity toward Human.

Quick Overview for CA2 antibody (ABIN576211)

Target: CA2 (Carbonic Anhydrase II (CA2))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This CA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunodiffusion (ID)

Product Details anti-CA2 Antibody

Specificity: Recognizes human carbonic anhydrase II, also known as Carbonate dehydratase II or Carbonic anhydrase C. Carbonic anhydrase II is a 259 amino acid ~30 kD enzyme essential for bone resorption and osteoclast differrentiation. Mutations in the CA2 gene has been identified as the cause of Osteopetrosis, autosomal recessive 3, a rare disease characterized by particularly dense bone, cerebral calcification and renal tubular acidisis. Product identity is confirmed by double diffusion vs. human CAII. No reactivity is seen in immunodiffusion against CAI.

Purification: Purified

Immunogen: Purified human carbonic anhydrase II (CAII) prepared from erythrocytes.

Type of Immunogen: Cells

Isotype: IgG

Application Details

Application Notes: Approved: ID, WB (1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Glycine buffered saline,  pH 7.4, 0.09 % sodium azide, 0.1 % EACA, 1 mM EDTA, 0.01 % benzamidine.

Preservative: Sodium azide, Benzamidine, EACA

Precaution of Use: This product contains Benzamidine and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Target Details for CA2

Target: CA2 (Carbonic Anhydrase II (CA2))

Alternative Name: CA2 / Carbonic Anhydrase II

Background: Name/Gene ID: CA2

Synonyms: CA2, CA-II, CAII, CAC, Car2, Carbonate dehydratase II, Carbonic anhydrase C, Carbonic anhydrase II, Carbonic dehydratase, Carbonic anhydrase 2, Carbonic anhydrase B

Gene ID: 760