Angiotensin I Converting Enzyme 1 antibody (PE)

Catalog No. ABIN602746

Product Details anti-Angiotensin I Converting Enzyme 1 Antibody (PE)

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Angiotensin I Converting Enzyme 1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: Recognizes human ACE/CD143.

Purification: Purified

Immunogen: Synthetic peptide corresponding to human ACE/CD143.

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Application Details

Application Notes: Approved: Flo

Usage: Suitable for use in Flow cytometry: Designed to quantitatively determine the percentage of cells bearing CD143 within a population and qualitatively determine the density of CD143 on cell surfaces by flow. cytometry. Washed cells are incubated with the phycoerythrin-labeled monoclonal antibody, which binds to cells expressing CD143. Unbound phycoerythrin-conjugated antibody is then washed from the cells. Cells expressing CD143 are fluorescently stained, with the intensity of. staining directly proportional to the density of expression of CD143. Cell surface expression of CD143 is determined by flow cytometric analysis using 488nm wavelength laser excitation. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 1.0 mL of PE-labeled antibody at a concentration of 25 μg/mL

Handling Advice: Avoid repeated freezing and thawing

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.

Target Details for Angiotensin I Converting Enzyme 1

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Alternative Name: ACE / DCP1 / CD143 (ACE Products)

Background: Name/Gene ID: ACE
Subfamily: Metallopeptidase M2
Family: Protease

Synonyms: ACE, ACE1, Angiotensin-converting enzyme, CD143, CD143 antigen, Carboxycathepsin, DIPEPTIDYL CARBOXYPEPTIDASE, DCP, Dipeptidyl carboxypeptidase I, ICH, Kininase II, MVCD3, Peptidyl-dipeptidase A, Peptidase P, DCP1, Dipeptidyl carboxypeptidase 1, Testicular ECA

Gene ID: 1636

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration