Angiotensin I Converting Enzyme 1 antibody (AA 592-701)

Catalog No. ABIN560577

Cited in 3+ publications. The Mouse Monoclonal anti-Angiotensin I Converting Enzyme 1 antibody (Clone 6A4) (ABIN560577) specifically detects Angiotensin I Converting Enzyme 1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Angiotensin I Converting Enzyme 1 antibody (AA 592-701) (ABIN560577)

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Angiotensin I Converting Enzyme 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6A4

Product Details anti-Angiotensin I Converting Enzyme 1 Antibody

Binding Specificity: AA 592-701

Purpose: Mouse monoclonal antibody raised against a partial recombinant ACE.

Sequence: RLATAMKLGF SRPWPEAMQL ITGQPNMSAS AMLSYFKPLL DWLRTENELH GEKLGWPQYN WTPNSDDFYN ETETKIFLQF YDQTGIWDHG APHLLPPSQA RGTREAPVYM

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ACE (AAH36375, 592 a.a. ~ 701 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Angiotensin I Converting Enzyme 1 antibody (ABIN560577)

Cougot, Cavalier, Thomas, Gillet: "The dual organization of P-bodies revealed by immunoelectron microscopy and electron tomography." in: Journal of molecular biology, Vol. 420, Issue 1-2, pp. 17-28, (2012) (PubMed).

Cargnello, Tcherkezian, Dorn, Huttlin, Maddox, Gygi, Roux: "Phosphorylation of the eukaryotic translation initiation factor 4E-transporter (4E-T) by c-Jun N-terminal kinase promotes stress-dependent P-body assembly." in: Molecular and cellular biology, Vol. 32, Issue 22, pp. 4572-84, (2012) (PubMed).

Dekanty, Romero, Bertolin, Thomas, Leishman, Perez-Perri, Boccaccio, Wappner: "Drosophila genome-wide RNAi screen identifies multiple regulators of HIF-dependent transcription in hypoxia." in: PLoS genetics, Vol. 6, Issue 6, pp. e1000994, (2010) (PubMed).

Target Details for Angiotensin I Converting Enzyme 1

Target: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Alternative Name: ACE

Background: Full Gene Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Synonyms: ACE1,CD143,DCP,DCP1,MGC26566

Gene ID: 1636

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration