CD137 antibody

Catalog No. ABIN610410

The Mouse Monoclonal anti-CD137 antibody (Clone 4B4-1) (ABIN610410) specifically detects CD137 in ELISA, FACS and Func. The antibody is reactive with Human samples.

Quick Overview for CD137 antibody (ABIN610410)

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD137 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Functional Studies (Func)

Clone: 4B4-1

Product Details anti-CD137 Antibody

Specificity: CD137 Molecule of about 35 kd from activated T cells.

Purification: Protein A purified

Immunogen: Ectodomain of recombinant human 4-1BB fusion protein.

Type of Immunogen: Fusion protein

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA, Flo, Func

Usage: Function: Blocks binding of CD137 huIg to Raji cells. Immobilized mAb induces TNF a production by monocytes. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Preservative: Azide free

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

Target Details for CD137

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Alternative Name: TNFRSF9 / 4-1BB / CD137

Background: Name/Gene ID: TNFRSF9
Family: TNF Receptor

Synonyms: TNFRSF9, 4-1BB ligand receptor, 4-1BB, CD137 antigen, CD137, Homolog of mouse 4-1BB, ILA, Receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CDw137

Gene ID: 3604

UniProt: Q07011

Pathways: Cancer Immune Checkpoints