SLC10A2 antibody (AA 50-99)

Catalog No. ABIN6746226

This Rabbit Polyclonal antibody specifically detects SLC10A2 in WB. It exhibits reactivity toward Human, Mouse, Dog, Horse and Monkey. It has been mentioned in 3+ publications

Quick Overview for SLC10A2 antibody (AA 50-99) (ABIN6746226)

Target: SLC10A2 (Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2))

Reactivity: Human, Mouse, Dog, Horse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC10A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC10A2 Antibody

Binding Specificity: AA 50-99

Specificity: Mouse SLC10A2

Predicted Reactivity: Percent identity by BLAST analysis: Dog (100%) Rat, Chicken (92%) Mouse (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa50-99 of mouse Slc10a2 (P70172, NP_035518). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Dog, Horse (100%), Rat, Elephant, Bat, Rabbit, Zebra finch, Chicken (92%), Galago, Marmoset, Guinea pig, Lizard (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-SLC10A2 antibody (ABIN6746226)

Vargas, Nore, Berglof, Heinonen, Mattsson, Smith, Mohamed: "Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx." in: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9351-7, (2002) (PubMed).

Rajantie, Ekman, Iljin, Arighi, Gunji, Kaukonen, Palotie, Dewerchin, Carmeliet, Alitalo: "Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium." in: Molecular and cellular biology, Vol. 21, Issue 14, pp. 4647-55, (2001) (PubMed).

Kaukonen, Lahtinen, Laine, Alitalo, Palotie: "BMX tyrosine kinase gene is expressed in granulocytes and myeloid leukaemias." in: British journal of haematology, Vol. 94, Issue 3, pp. 455-60, (1996) (PubMed).

Target Details for SLC10A2

Target: SLC10A2 (Solute Carrier Family 10 (Sodium/bile Acid Cotransporter Family), Member 2 (SLC10A2))

Alternative Name: SLC10A2 / ASBT

Background: Name/Gene ID: SLC10A2
Subfamily: Bile acid:sodium symporter
Family: Transporter

Synonyms: SLC10A2, ASBT, ISBT, NTCP2, IBAT, PBAM

Gene ID: 6555

NCBI Accession: NP_035518

UniProt: Q12908