SLC16A3 antibody (AA 40-89)

Catalog No. ABIN6746227

There are 3+ publications for this product available. The Rabbit Polyclonal anti-SLC16A3 antibody is suitable to detect SLC16A3 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for SLC16A3 antibody (AA 40-89) (ABIN6746227)

Target: SLC16A3 (Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC16A3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC16A3 Antibody

Binding Specificity: AA 40-89

Specificity: Mouse SLC16A3

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Xenopus (92%) Mouse, Rat, Dog, Bovine, Rabbit, Zebrafish (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa40-89 of mouse Slc16a3 (P57787, NP_109621). Percent identity by BLAST analysis: Human, Gorilla, Mouse (100%), Orangutan, Gibbon, Elephant, Horse, Opossum, Zebra finch, Platypus, Xenopus (92%), Monkey, Marmoset, Rat, Hamster, Dog, Bovine, Rabbit, Guinea pig, Turkey, Chicken, Zebrafish (85%), Panda (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-SLC16A3 antibody (ABIN6746227)

Vargas, Nore, Berglof, Heinonen, Mattsson, Smith, Mohamed: "Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx." in: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9351-7, (2002) (PubMed).

Rajantie, Ekman, Iljin, Arighi, Gunji, Kaukonen, Palotie, Dewerchin, Carmeliet, Alitalo: "Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium." in: Molecular and cellular biology, Vol. 21, Issue 14, pp. 4647-55, (2001) (PubMed).

Kaukonen, Lahtinen, Laine, Alitalo, Palotie: "BMX tyrosine kinase gene is expressed in granulocytes and myeloid leukaemias." in: British journal of haematology, Vol. 94, Issue 3, pp. 455-60, (1996) (PubMed).

Target Details for SLC16A3

Target: SLC16A3 (Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3))

Alternative Name: SLC16A3 / MCT4

Background: Name/Gene ID: SLC16A3
Subfamily: Monocarboxylic acid transporter
Family: Transporter

Synonyms: SLC16A3, MCT 3, MCT-4, MCT3, MCT4, Monocarboxylate transporter 4, MCT-3, Monocarboxylate transporter 3, MCT 4

Gene ID: 9123

NCBI Accession: NP_109621

UniProt: O15427

Pathways: Warburg Effect