H2AFY2 antibody (Middle Region)

Catalog No. ABIN630681

The Rabbit Polyclonal anti-H2AFY2 antibody (ABIN630681) specifically detects H2AFY2 in WB. The antibody is reactive with Human samples.

Quick Overview for H2AFY2 antibody (Middle Region) (ABIN630681)

Target: H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFY2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-H2AFY2 Antibody

Binding Specificity: Middle Region

Specificity: H2 AFY2 antibody was raised against the middle region of H2 FY2

Purification: Affinity purified

Immunogen: H2 AFY2 antibody was raised using the middle region of H2 FY2 corresponding to a region with amino acids PRIHPELLAKKRGTKGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRT

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

H2AFY2 Blocking Peptide, (ABIN5613918), is also available for use as a blocking control in assays to test for specificity of this H2AFY2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of H0 FY2 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for H2AFY2

Target: H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))

Alternative Name: H2AFY2

Background: H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.

Molecular Weight: 40 kDa (MW of target protein)